|
|
GA (Tabun)
Ethyl phosphorodimethylamido-cyanidate
GA is a volatile, liquid anticholinesterase nerve agents that reacts
irreversibly with the enzyme cholinesterase, thereby permitting a deleterious
accumulation of acetylcholine at nerve endings, which can lead to rapid death.
Tabun (GA) is a neurotoxic agent with an i.v. LD50 in
monkeys of 50 mg/kg and in rabbits of 63 mg/kg17.
GA causes runny nose, tightness of chest, dimness of vision and
pinpointing of the eye pupils, difficulty in breathing, drooling and excessive sweating,
nausea, vomiting, cramps, involuntary defecation and urination, twitching, jerking and
staggering, headache, drowsiness, coma and convulsions, followed by cessation of breathing
and death.
|