Molecular Formula: C2H3ClF2
Molecular Weight: 100.50
Beilstein Registry Number: 1731584
Beilstein Source Citation: 4-01-00-00127
Synonyms: CFC 142b; 1-Chloro-1,1-difluoroethane; Chlorodifluoroethanes (DOT);
Chloroethylidene fluoride; alpha-Chloroethylidene fluoride; Difluorochloroethanes (DOT);
1,1-Difluoro-1-chloroethane; FC142b; Fluorocarbon FC142b; Freon 142; Freon 142b; Genetron
101; Genetron 142b; Gentron 142B; Hydrochlorofluorocarbon 142b; Isotron 142b;
Monochlorodifluoroethane; R142B (DOT); UN2517 (DOT)
Compound Class: Mutagen; Reproductive Effector
Wiswesser Line Notation: GXFF
Record Date: 199712
MUTATION DATA:
Mutation in microorganisms Salmonella typhimurium 50 pph/24H TXAPA9 72,15,1984
REPRODUCTIVE EFFECTS DATA:
Pre-implantation mortality Inhalation Rat TCLo 1000 ppm/6H 3-15D preg NTIS** OTS0555347
TOXICITY EFFECTS DATA:
- Inhalation Rat LC50 2050 gm/m3/4H 85GMAT -,53,1982
- Inhalation Mouse LC50 1758 gm/m3/2H 85GMAT -,53,1982
OTHER MULTIPLE DOSE EFFECTS DATA:
Evidence of thyroid hypofunction; Inhalation Rat TCLo 500 gm/m3/4H/4W-I TPKVAL
9,175,1967
Lungs, Thorax, or Respiration--Other changes; Death in the "U" date type
field; Inhalation Rat TCLo 10 pph/16H/9D-I AIHOAX 2(3),335,1950
STANDARDS AND REGULATIONS:
DOT-HAZARD 2.1; LABEL:FLAMMABLE GAS CFRGBR 49,172.101,1992
OEL-GERMANY TWA 1000 ppm (4170 mg/m3) JAN 1993
OEL-HUNGARY TWA 100 mg/m3;STEL 200 mg/m3 JAN 1993
OEL-RUSSIA STEL 3000 mg/m3 JAN 1993
NIOSH CRITERIA DOCUMENTS:
NOHS 1974: HZD 82201; NIS 1; TNF 11; NOS 3; TNE 357
NTP, NIOSH, EPA STATUS:
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, SEPTEMBER 1997
MUTATION EFFECTS JOURNAL REFERENCES:
TXAPA9 Toxicology and Applied Pharmacology. Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802 V.1- 1959-
REPRODUCTIVE EFFECTS JOURNAL REFERENCES:
NTIS** National Technical Information Service. Springfield, VA 22161 Formerly U.S.
Clearinghouse for Scientific & Technical Information.
TOXICITY EFFECTS JOURNAL REFERENCES:
85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure,
Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
OTHER MULTIPLE DOSE EFFECTS JOURNAL REFERENCES:
AIHOAX Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.1-2 3,
1950. For publisher information, see AEHLAU.
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New
Industrial Chemical Substances. For English translation, see TNICS*. Izdatel'stvo
Meditsina, Moscow, USSR No.1- 1961-
STANDARDS & REGULATIONS JOURNAL REFERENCES:
CFRGBR Code of Federal Regulations. U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402
DATA PRESENT: Mutation Effects; Reproductive Effects; Toxicity Effects; Other Multiple
Dose Effects; Standards and Regulations; NIOSH Criteria Documents; NTP, NIOSH, EPA Status
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